Bio-Analytical Mass Spectrometry
Gabelica group
OTHER SIGNIFICANT PUBLICATIONS
69. V. Gabelica
Mass Spectrometry and Gas‐Phase Chemistry of Non‐Covalent Complexes
Christoph A. Schalley and Andreas Springer, Authors D.M. Desiderio and N.M. Nibbering, Series Editors John Wiley and Sons, Inc. Hoboken, NJ ISBN: 978‐0‐470‐13115‐2 2009, Hardcover, 571 pages",
J. Am. Soc. Mass Spectrom. (2012), 23(3), 570‐571.
68. B. Pagano, S. Cosconati, V. Gabelica, L. Petraccone, S. De Tito, L. Marinelli, V. La Pietra, F. Saverio di Leva, I. Lauri, R. Trotta, E. Novellino, C. Giancola, A. Randazzo
State‐of‐the‐art methodologies for thediscovery and characterization of DNA G‐Quadruplex binders
Curr. Pharm. Des. (2012), 18(14), 1880‐1899.
67. N.M. Smith, S. Amrane, F. Rosu, V. Gabelica, J.L. Mergny
Mercury–thymine interaction with a chair type G‐quadruplex architecture
Chem. Commun. (2012), 48, 11464‐11466.
66. J. Zhou, A. Bourdoncle, F. Rosu, V. Gabelica, J.L. Mergny
Tri‐G‐quadruplex: Controlled assembly of a G‐quadruplex Structure from Three G‐rich Strands
Angew. Chem. Int. Ed. (2012), 51(44), 11002‐11005. (selected by Faculty of 1000)
65. F. Rosu, V. Gabelica, E. De Pauw, R. Antoine, M. Broyer, P. Dugourd
UV Spectroscopy of DNA Duplexand Quadruplex Structures in the Gas Phase
J. Phys. Chem. A (2012) 116, 5383‐5391.
64. L. Joly, F. Rosu, V. Gabelica
d(TGnT) DNA sequences do not necessarily form tetramolecular G‐quadruplexes
Chem. Commun. (2012) 48, 8386‐8388.
63. R. Ferreira, M. Alvira, A. Aviñó, I. Gómez‐Pinto, C. González, V. Gabelica, R. Eritja
Synthesis andStructural Characterization of Stable Branched DNA G‐Quadruplexes Using the Trebler Phosphoramidite
ChemistryOPEN (2012), 1(2), 106‐114.
62. R. Ferreira, A. Marchand, V. Gabelica
Mass spectrometry and ion mobility spectrometry of G‐quadruplexes. A study of solvent effects on dimer formation and structural transitions in the telomeric DNA sequence d(TAGGGTTAGGGT)
Methods (2012), 57(1), 56‐63.
61. A. Arcella, G.Portella, M.L. Ruiz, R. Eritja, M. Vilaseca, V. Gabelica, M. Orozco
The structure of triplex DNA in the gas phase
J. Am. Chem. Soc. (2012), 134(15), 6596‐6606.
60. E. Largy, F. Hamon, F. Rosu, V. Gabelica, E. De Pauw, A. Guédin, J.‐L. Mergny, M.‐P. Teulade‐Fichou
Tridentate N‐Donor Palladium(II) Complexes as Efficient Coordinating Quadruplex DNA Binders
Chem. Eur. J. (2011), 17, 13274‐13283.
59. D. Delvaux, M.R.V.S. Murty, V. Gabelica, B. Lakaye, V.V. Lunin, T. Skarina, O. Onopriyenko, G. Kohn, P.Wins, E. De Pauw, L. Bettendorff
A specific inorganic triphosphatase from Nitrosomonas europaea: structure and catalytic mechanism
J. Biol. Chem. (2011), 286(39), 34023‐34035.
58. N. Borbone, J. Amato, G. Oliviero, V. D’Atri, V. Gabelica, E. De Pauw, G. Piccialli, L. Mayol
"d(CGGTGGT) forms an octameric parallel G‐quadruplex via stacking of unusual G(:C):G(:C):G(:C):G(:C) octads"
Nucleic Acids Res. (2011), 39(17), 7848‐7857.
57. D. Morsa, V. Gabelica, E. De Pauw
Effective temperature of ions in traveling wave ion mobility spectrometry
Anal. Chem. (2011), 83(14), 5775‐5782.
56. J. Amato, B. Pagano, N. Borbone, G. Oliviero, V. Gabelica, E. De Pauw, S. D'Errico, V. Piccialli, M. Varra, C. Giancola, G. Piccialli, L. Mayol
Targeting G‐Quadruplex Structure in the Human c‐Kit Promoter with Short PNA Sequences
Bioconj. Chem. (2011), 22(4), 654‐663.
55. V. Gabelica
Determination of equilibrium association constants of ligand‐DNA complexes byelectrospray mass spectrometry
Methods Mol Biol. (2010), 613, 89‐101.
54. C.M. Lombardo, I.S. Martínez, S. Haider, V. Gabelica, E. De Pauw, J.E. Moses, S. Neidle
Structure based design of selective high‐affinity telomeric quadruplex‐binding ligands
Chem. Commun. (2010), 46(48), 9116 ‐ 9118.
53. K. Demeure, V. Gabelica, E. De Pauw
New Advances in the Understanding of the In‐Source Decay Fragmentation of Peptides in MALDI‐TOF‐MS
J. Am. Soc. Mass Spectrom. (2010), 21(11), 1906‐1917.
52. F. Rosu, V. Gabelica, L. Joly, G. Grégoire, E. De Pauw
Zwitterionic i‐motif structures are preserved inDNA negatively charged ions produced by electrospray mass spectrometry
Phys. Chem. Chem. Phys. (2010), 12, 13448‐13454.
51. F. Rosu, V. Gabelica, N. Smargiasso, G. Mazzucchelli, K. Shin‐ya, E. De Pauw
Cation involvement intelomestatin binding to G‐quadruplex DNA
J. Nucleic Acid. (2010), 121259 (7 pages).
50. G.W. Collie, G.N. Parkinson, S. Neidle, F. Rosu, E. De Pauw, V. Gabelica
Electrospray mass spectrometry of telomeric RNA (TERRA) reveals the formation of stable multimeric G‐quadruplex structures
J. Am. Chem. Soc. (2010), 132 (27), 9328–9334.
49. F. Rosu, V. Gabelica, H. Poncelet, E. De Pauw
Tetramolecular G‐quadruplex formation pathways studied by electrospray mass spectrometry
Nucleic Acid. Res. (2010), 38(15), 5217‐5225.
48. G. Collie, A.P. Reszka, S.M. Haider, V. Gabelica, G.N. Parkinson, S. Neidle
Selectivity in small molecule binding to human telomeric RNA and DNA quadruplexes
Chem. Commun. (2009), 48, 7482‐7484.
47. N. Smargiasso, V. Gabelica, C. Damblon, F. Rosu, E. De Pauw, MP. Teulade‐Fichou, JA. Rowe, A. Claessens
Putative DNA G‐quadruplex formation within the promoters of Plasmodium falciparum var genes
BMC Genomics (2009) 10, 362.
46. V. Gabelica, F. Rosu, E. De Pauw
A Simple Method to Determine Electrospray Response Factors ofNoncovalent Complexes
Anal. Chem., (2009), 81(16), 6708‐6715.
45. C. Kinet, V. Gabelica, D. Balbeur, E. De Pauw
Electron detachment dissociation (EDD) pathways in oligodeoxynucleotides
Int. J. Mass Spectrom., (2009), 283: 206‐213.
44. J. Amato, G. Oliviero, E. De Pauw, V. Gabelica
Hybridization of Short Complementary PNAs to G‐Quadruplex Forming Oligonucleotides: an Electrospray Mass Spectrometry Study
Biopolymers, (2009), 91(4), Special Issue “Advances in the Investigation of Nucleic Acids and Nucleic Acid Assemblies”, 244‐255.
43. F. Rosu, E. De Pauw, V. Gabelica
Electrospray Mass Spectrometry to Study Drug‐Nucleic Acid Interactions
Biochimie (2008), 90(7), Special issue "Targeting DNA Part I", 1074‐1087.
42. G.D. Mazzucchelli , V. Gabelica , N. Smargiasso , M. Fleron , W. Ashimwe , F. Rosu , MC. De Pauw‐Gillet, JF. Riou, E. De Pauw
Proteome alteration induced by hTERT transfection of human fibroblast cells
Proteome Sci. (2008), 6:12.
41. M. Bahr, V. Gabelica, A. Granzhan, E. Weinhold, M.P. Teulade‐Fichou
Selective recognition ofpyrimidine‐pyrimidine DNA mismatches by distance‐constrained macrocycle bisintercalators
Nucleic Acids Res. (2008), 36, 5000‐5012.
40. N. Smargiasso, F. Rosu, W. Hsia, P. Colson, E.S. Baker, M.T. Bowers, E. De Pauw, V. Gabelica
G‐Quadruplex DNA Assemblies: Loop Length, Cation Identity and Multimer Formation
J. Am. Chem. Soc. (2008), 130(31), 10208‐10216.
39. D. Monchaud, C. Allain, H. Bertrand, N. Smargiasso, F. Rosu, V. Gabelica, A. De Cian, J.‐L. Mergny, M.‐P. Teulade‐Fichou
Ligands playing musical chairs with G‐quadruplex DNA: A rapid and simple displacement assay for identifying selective G‐quadruplex binders
Biochimie (2008), 90(8), Special issue "Targeting DNA Part II", 1207‐1223.
38. V. Gabelica, F. Rosu, E. De Pauw, J. Lemaire, J.C. Gillet, J.C. Poully, F. Lecomte, G. Grégoire, J.P. Schermann, C. Desfrançois
Infrared signature of DNA G‐Quadruplexes in the gas phase
J. Am. Chem. Soc. (2008), 130(6), 1810‐1811.
37. F. Rosu, V. Gabelica, E. De Pauw, P. Mailliet, J.L. Mergny
Cooperative 2:1 binding of a bisphenothiazine to duplex DNA
ChemBioChem (2008), 9, 849‐852.
36. V. Gabelica, F. Rosu, E. De Pauw, R. Antoine, T. Tabarin, M. Broyer, P. Dugourd
Electron Photodetachment Dissociation of DNA Anions with Covalently or Noncovalently Bound Chromophores
J. Am. Soc. Mass Spectrom. (2007), 18, 1990‐2000.
35. K. Demeure, L. Quinton, V. Gabelica, E. De Pauw
Rational Selection of the Optimum MALDI Matrix forTop‐down Proteomics by In‐Source Decay
Anal. Chem. (2007), 79(22), 8678‐8685.
34. L. Quinton, K. Demeure, R. Dobson, N. Gilles, V. Gabelica, E. De Pauw
New method for characterizing highly disulfide‐bridged peptides in complex mixtures: Application to toxin identification from crude venoms
J. Proteome Res. (2007), 6(8), 3216‐3223.
33. J. Gros, F. Rosu, S. Amrane, A. De Cian, V. Gabelica, L. Lacroix, J.‐L. Mergny
Guanines are a quartet’s best friend: impact of base substitutions on the kinetics and stability of tetramolecular quadruplexes
Nucleic Acids Res. (2007), 35, 3064‐3075.
32. F. Rosu, C.‐H. Nguyen, E. De Pauw, V. Gabelica
Ligand binding mode to duplex and triplex DNA assessed by combining electrospray tandem mass spectrometry and molecular modeling
J. Am. Soc. Mass Spectrom. (2007), 18(6), 1052‐1062. (issue cover)
31. V. Gabelica, F. Rosu, T. Tabarin, C. Kinet, R. Antoine, M. Broyer, E. De Pauw, P. Dugourd
Base‐Dependent Electron Photodetachment from Negatively Charged DNA Strands upon 260‐nm Laser Irradiation
J. Am. Chem. Soc. (2007), 129, 4706‐4713.
30. V. Gabelica, E.S. Baker, M.P. Teulade‐Fichou, E. De Pauw, M.T. Bowers
Stabilization and Structure of Telomeric and c‐myc Region Intramolecular G‐Quadruplexes: The Role of Central Cations and Small Planar Ligands
J. Am. Chem. Soc. (2007), 129, 895‐904.
29. V. Gabelica, T. Tabarin, R. Antoine, F. Rosu, I. Compagnon, M. Broyer, E. De Pauw, P. Dugourd
Electron Photodetachment Dissociation of DNA Polyanions in a Quadrupole Ion Trap Mass Spectrometer
Anal. Chem. (2006), 78, 6564‐6572.
28. A. Louati, J. Spraula, V. Gabelica, P. Kuhn, D. Matt
Electrochemical study of two tris‐O‐substituted calix[4]arenes: 25,27‐Dipropoxy‐26‐hydroxy‐28‐benzoyloxycalix[4]arene(partial cone) and 25,27‐dibenzyl‐26‐hydroxy‐28‐benzoyloxy‐calix[4]arene(partial cone). Electrosynthesis of the corresponding calix[4]arene‐monoquinones
Electrochem. Commun. (2006), 8(5), 761‐766.
27. E.S. Baker, S.L. Bernstein, V. Gabelica, E. De Pauw, M.T. Bowers
G‐Quadruplexes in Telomeric Repeats Are Conserved in a Solvent‐Free Environment
Int. J. Mass Spectrom. (2006), 253(3) Special Issue "Solution vs. Gas Phase Biomolecule Structure", 225‐237.
26. F. Rosu, S. Pirotte, E. De Pauw, V. Gabelica
Positive and Negative ion Mode ESI‐MS and MS/MS for Studying Drug‐DNA Complexes
Int. J. Mass Spectrom. (2006), 253(3) Special Issue "Solution vs. Gas Phase Biomolecule Structure", 156‐171.
25. E. Schultz, M. Karas, F. Rosu, V. Gabelica
Influence of the Matrix on Analyte Fragmentation in Atmospheric Pressure MALDI
J. Am. Soc. Mass Spectrom. (2006), 17(7), 1005‐1013.
24. V. Gabelica, E. De Pauw
Internal Energy and Fragmentation of Ions Produced in Electrospray Sources
Mass Spectrom. Rev. (2005), 24, 566‐587.
23. A. Louati, R. Vataj, V. Gabelica, M. Lejeune, D. Matt
Formation of upper rim acylated calix[4]arenes using a sacrificial zinc anode
Tetrahedron Lett. (2005), 46, 7499‐7502.
22. L. Guittat, A. De Cian, F. Rosu, V. Gabelica, E. De Pauw, E. Delfourne, J.‐L. Mergny
Ascididemin andmeridine stabilise G‐quadruplexes and inhibit telomerase in vitro
Biochim. Biophys. Acta (2005), 1724, 375‐384.
21. V. Gabelica, F. Rosu, M. Witt, G. Baykut, E. De Pauw
Fast gas‐phase H/D exchange observed for a G‐quadruplex DNA
Rapid Commun. Mass Spectrom. (2005), 19, 201‐208.
20. V. Henrotte, S. Laurent, V. Gabelica, L. Van der Elst, E. De Pauw, R.N. Muller
Investigation of non‐covalent interactions between paramagnetic complexes and human serum albumin by electrospray mass spectrometry
Rapid Commun. Mass Spectrom. (2004), 18, 1919‐1924.
19. V. Gabelica, E. Schulz, M. Karas
Internal Energy build‐up in matrix‐assisted laser desorption/ionization
J. Mass Spectrom. (2004), 39, 579‐593.
18. V. Gabelica, E. De Pauw, M. Karas
Influence of the capillary temperature and the source pressure on the internal energy distribution of electrosprayed ions
Int. J. Mass Spectrom. (2004), 231, 189‐195.
17. F. Rosu, V. Gabelica, K. Shin‐ya, E. De Pauw
Telomestatin‐induced stabilization of the human telomeric DNA quadruplex monitored by electrospray mass spectrometry
Chem. Commun. (2003), 2072‐2073.
16. V. Gabelica, M. Karas, E. De Pauw
Calibration of ion effective temperatures achieved by resonant activation in a quadrupole ion trap
Anal. Chem. (2003), 75, 5152‐5159.
15. J.F. Greisch, V. Gabelica, F. Remacle, E. De Pauw
Thermometer ions for matrix‐enhanced laser desorption/ionisation internal energy calibration
Rapid Commun. Mass Spectrom. (2003), 17, 1847‐1854.
14. L. Guittat, P. Alberti, F. Rosu, S. Van Miert, E. Thetiot, L. Pieters, V. Gabelica, E. De Pauw, A. Ottaviani,J.‐F. Riou, J.‐L. Mergny
Interactions of cryptolepine and neocryptolepine with unusual DNA structures
Biochimie (2003), 85, 535‐547. (issue cover)
13. V. Gabelica, N. Galic, F. Rosu, C. Houssier, E. De Pauw
Influence of response factors on determining equilibrium association constants of non‐covalent complexes by electrospray ionization mass spectrometry
J. Mass Spectrom., (2003), 38, 491‐501.
12. C. Carrasco, F. Rosu, V. Gabelica, C. Houssier, E. De Pauw, C. Garbay‐Jaureguiberry, B. Roques, D. W.Wilson, J. B. Chaires, M. J. Waring, C. Bailly
Tight binding of the antitumor drug ditercalinium to quadruplex DNA
ChemBioChem., (2002), 3, 1235‐1241.
11. F. Rosu, V. Gabelica, P. Colson, E. De Pauw
Triplex and Quadruplex DNA Structures Studied by Electrospray Mass Spectrometry
Rapid Commun. Mass Spectrom., (2002) 16, 1729‐1736.
10. V. Gabelica, C. Vreuls, P. Filée, V. Duval, B. Joris, E. De Pauw
Advantages and Drawbacks of Nanospray for Studying Noncovalent Protein‐DNA Complexes by Mass Spectrometry
Rapid Commun. Mass Spectrom., (2002) 16, 1723‐1728.
9. F. Rosu, V. Gabelica, C. Houssier, E. De Pauw
Determination of Affinity, Stoichiometry and Sequence Selectivity of Minor Groove Binder Complexes with Double‐Stranded Oligodeoxynucleotides by Electrospray Ionization Mass Spectrometry
Nucleic Acids Res. (2002) 30, e82 (9 pages, open access article).
8. V. Gabelica, N. Galic, E. De Pauw
On the Specificity of Cyclodextrin Complexes Detected by Electrospray Mass Spectrometry
J. Am. Soc. Mass Spectrom. (2002) 13, 946‐953.
7. V. Gabelica, E. De Pauw
Collision‐induced dissociation of 16‐mer DNA duplexes with various sequences: evidence for conservation of the double helix conformation in the gas phase
Int. J. Mass Spectrom. (2002) 219, 151‐159.
6. R. Vastaj, H. Ridaoui, A. Louati, V. Gabelica, S. Steyer, D. Matt
First synthesis of “1,2‐diquinone‐calix[4]arene”. Interaction of its reduced form with Ag+
J. Electroanal. Chem. (2002) 519, 123‐129.
5. V. Gabelica, E. De Pauw,
Comparison of the Collision‐Induced Dissociation of Duplex DNA at Different Collision Regimes: Evidence for a Multistep Dissociation Mechanism
J. Am. Soc. Mass Spectrom. (2002) 13, 91‐98.
4. V. Gabelica, D. Lemaire, O. Laprévote, E. De Pauw
Kinetics of Solvent Addition on Electrosprayed Ions in an Electrospray Source and in a Quadrupole Ion Trap
Int. J. Mass Spectrom. (2001) 210/211, 113‐119.
3. V. Gabelica, E. De Pauw
Comparison between Solution Phase Stability and Gas Phase Kinetic Stability of Oligodeoxynucleotide Duplexes
J. Mass Spectrom. (2001) 36(4), 397‐402.
2. V. Gabelica, F. Rosu, C. Houssier, E. De Pauw
Gas Phase Thermal Denaturation of Oligonucleotide Duplex and Complexes with Minor Groove Binders
Rapid Commun. Mass Spectrom. (2000) 14(6), 464‐467.
1. V. Gabelica, E. De Pauw, F. Rosu,
The Interaction between Antitumor Drugs and a Double‐stranded Oligonucleotide Studied by Electrospray Ionization Mass Spectrometry
J. Mass. Spectrom (1999). 34(12), 1328‐1337.